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KMID : 0364019920250121516
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Korean Journal of Thoracic and Cardiovascular Surgery
1992 Volume.25 No. 12 p.1516 ~ p.1522
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Extended Thymectomy in Myasthenia Gravis
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조광조
이형렬/김원종/정황규/성시찬
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Abstract
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Thirty patients with myasthenis gravis (MG) underwent transternal extended thymectomy between 1983 and 1992 in Pusan National University Hospital. The age of patients was 11 to 62 years (mean; 35.2 years) with female dominant (M:F=1:4).
According to modified Osserman classification, group Ⅰ was in 6, ⅡA in 7, ⅡB in 13, Ⅲ in 2, Ⅳ in 2 patients respectively. Their clinical response to thymectomy was evaluated. The follow-up period ranged from 2 months to 9.5 years (average;
51.3
months). Fourteen patients (13.3%) had remission and eleven (43.3%) were improved after operation; half of patients were benefited from operation. Twenty patients had thymic hyperplasia and seven had non-infiltrating thymoma. In thymomatous MG
one
patient had remission and five were improved.
Postoperative death was in a female patient. The cause of death was respiratory failure in the severe generalized MG preoperatively.
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